Lymphoma PDX Models

Identifying robust preclinical models for lymphoma is essential for the development of new therapies targeting this disease. Patient-derived xenograft (PDX) models provide a predictive preclinical model with true representation of the human heterogeneity providing an accurate approach to predicting an agent’s efficacy prior to entering the clinic. The Crown Bioscience lymphoma PDX collection consists of many models, including both primary and metastatic models. More

PDX offer the most translational preclinical model for efficacy screening in cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, PDX models reflect the heterogeneity and diversity of the human patient population. PDX give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials. Crown Bioscience’s HuPrime® PDX models are well characterized for pathology, growth characteristics, and are also genetically/genomically annotated for gene expression, gene copy number, mutations, and fusions.
MODEL NUMBERCANCER SUBTYPE # per page
LY0257NHL (DLBCL, ABC, MYD88 L265P)CLICK TO VIEW
LY14019NHLCLICK TO VIEW
LY2104EBV transformed lymphomaCLICK TO VIEW
LY2118EBV transformed lymphomaCLICK TO VIEW
LY2201LymphomaCLICK TO VIEW
LY2214NHL (DLBCL, GCB)CLICK TO VIEW
LY2219EBV transformed lymphomaCLICK TO VIEW
LY2240EBV transformed lymphomaCLICK TO VIEW
LY2264NHL (DLBCL, ABC, MYD88 L265P)CLICK TO VIEW
LY2266NHL (B cell, ABC/GCB)CLICK TO VIEW
LY2298B cell lymphoma (ABC/GCB, MYD88 L265P)CLICK TO VIEW
LY2301NHL (DLBCL, ABC)CLICK TO VIEW
LY2310B cell lymphomaCLICK TO VIEW
LY2318NHL (DLBCL, GCB)CLICK TO VIEW
LY2345NHL (DLBCL, ABC/GCB)CLICK TO VIEW
LY3071EBV transformed lymphomaCLICK TO VIEW
LY3148Burkitt lymphomaCLICK TO VIEW
LY3463B cell lymphomaCLICK TO VIEW
LY3604NHL (DLBCL, ABC/GCB)CLICK TO VIEW
LY3654Follicular lymphomaCLICK TO VIEW

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