Lung Cancer Tumor Homograft Models

Lung cancer is a heterogeneous and complex disease. Predictive preclinical models are required to advance novel treatments and provide better combination strategies. Our tumor homografts are transplants of GEMM lung tumors into syngeneic hosts, providing robust models with relevant molecular pathology and rich TME.

MODEL CANCER TYPE ORIGINAL GEMM MUTATION CARCINOGEN models per page
mLU6044Lung CancerKras (G12D); P53-/-VIEW MODEL
mLU6045Lung CancerKras (G12D); P53-/-VIEW MODEL
mLU6050Lung CancerUrethaneVIEW MODEL
mLU6051Lung CancerUrethaneVIEW MODEL
mLU6054Lung CancerKRAS (G12D); PtenFlox/FloxVIEW MODEL
mLU6073Lung CancerPTENFlox/Flox; P53-/-VIEW MODEL
mLU6075Lung CancerP53-/-VIEW MODEL
mLU6081Lung CancerUrethaneVIEW MODEL
mLU6131Lung CancerUrethaneVIEW MODEL
mLU6132Lung CancerUrethaneVIEW MODEL
mLU6133Lung CancerUrethaneVIEW MODEL
mLU6134Lung CancerUrethaneVIEW MODEL
mLU6136Lung CancerKRAS (G12D); PtenFlox/FloxVIEW MODEL