Lung Cancer Tumor Homograft Models

Lung cancer is a heterogeneous and complex disease. Predictive preclinical models are required to advance novel treatments and provide better combination strategies. Our tumor homografts are transplants of GEMM lung tumors into syngeneic hosts, providing robust models with relevant molecular pathology and rich TME.

MODEL NUMBER ORIGINAL GEMM MUTATION CARCINOGEN # per page
mLU6044Kras (G12D); P53-/-CLICK TO VIEW
mLU6045Kras (G12D); P53-/-CLICK TO VIEW
mLU6050UrethaneCLICK TO VIEW
mLU6051UrethaneCLICK TO VIEW
mLU6054KRAS (G12D); PtenFlox/FloxCLICK TO VIEW
mLU6073PTENFlox/Flox; P53-/-CLICK TO VIEW
mLU6075P53-/-CLICK TO VIEW
mLU6081UrethaneCLICK TO VIEW
mLU6131UrethaneCLICK TO VIEW
mLU6132UrethaneCLICK TO VIEW
mLU6133UrethaneCLICK TO VIEW
mLU6134UrethaneCLICK TO VIEW
mLU6136KRAS (G12D); PtenFlox/FloxCLICK TO VIEW