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Patient-Derived Xenograft (PDX) Models

Models » Patient-Derived Xenograft (PDX)

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Patient-Derived Xenograft (PDX) Models

CrownBio’s PDX collection consists of over 2,500 well-characterized models that supports translational preclinical oncology research for over thirty human cancer types. Including rare indications and highly-specific molecular targets. Click a cancer type below to learn more about our models.

  • Acute Lymphoblastic LeukemiaAcute Lymphoblastic Leukemia
  • Acute Myeloid LeukemiaAcute Myeloid Leukemia
  • Adrenal Gland CancerAdrenal Gland Cancer
  • Bladder CancerBladder Cancer
  • Brain CancerBrain Cancer
  • Breast CancerBreast Cancer
  • Cervical CancerCervical Cancer
  • CholangiocarcinomaCholangiocarcinoma
  • Colorectal CancerColorectal Cancer
  • Esophageal CancerEsophageal Cancer
  • Gallbladder CancerGallbladder Cancer
  • Gastric CancerGastric Cancer
  • GISTGIST
  • Head and Neck CancerHead and Neck Cancer
  • Kidney CancerKidney Cancer
  • Liver CancerLiver Cancer
  • Lung CancerLung Cancer
  • LymphomaLymphoma
  • MelanomaMelanoma
  • MesotheliomaMesothelioma
  • Metastatic CarcinomaMetastatic Carcinoma
  • Mixed Mullerian CancerMixed Mullerian Cancer
  • Ovarian CancerOvarian Cancer
  • Pancreatic CancerPancreatic Cancer
  • Prostate CancerProstate Cancer
  • SarcomaSarcoma
  • Skin CancerSkin Cancer
  • Testical CancerTestical Cancer
  • Thyroid CancerThyroid Cancer
  • Uterine CancerUterine Cancer

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Models

  • Cell Line Derived Xenograft
  • HSC and PBMC Humanized
  • Human Target Knock-In ( HuGEMMTM )
  • Patient-Derived Xenograft ( HuPrimeTM )
  • Syngeneic
  • Tumor Homograft ( MuPrimeTM )
  • In Vivo - Autoimmune

Inflammation

  • (IBD) - Inflammatory Bowel Disease
  • (RA) - Rheumatoid Arthritis

CVMD

Home

Cardiovascular Disease

  • NHP
  • Rodent

Diabetes

  • NHP
  • Rodent

NAFLD/NASH

  • NHP
  • FATZO

Obesity

  • NHP
  • Rodent

Renal Disease

  • NHP
  • Rodent

Safety/Toxicology

  • Non-GLP Toxicology
  • Safety Pharmacology

Oncology

In Vivo Services

  • Breast Cancer Preclinical Models
  • Cell Line Derived Xenograft Models
  • Cell Line and Model Authentication
  • Custom Tumor Model Development
  • Immuno-Oncology Model
  • MuScreen
  • Orthotopic and Bioluminescent Models
  • Patient-Derived Xenograft Models (HuPrime/HuKemia)
  • Prostate Cancer Preclinical Models
  • Radiation Therapy
  • Syngeneic Tumor Models

In Vitro Services

  • Cell Based Screening
    • CrownSyn
  • Cell Line and Model Authentication
  • Cell Line Panels
  • Flow Cytometry Platform
  • Immuno-Oncology
  • OmniScreen Cell Based Screening Service
  • Organoids
  • PDX-Derived Cell Lines

Organoids

  • Cell Line and Model Authentication
  • Organoid and Immune Cell Co-Culture

Ex Vivo Services

  • 3D Assays
  • Tumor Microarrays

Immuno-Oncology

  • CAR-T Cell Therapy Models
    • Cell Line Derived Xenografts Targeting CD19
    • PDX
  • Humanized Models
    • Hematopoietic Stem Cell (HSC)-PDX
    • MiXeno
  • Human Target Knock-In Models
    • HuGEMM
    • HuCELL
  • Murine Immunity Model Services
    • Tumor Homograft Models
    • Syngeneic tumor Models
    • MuScreen
    • Mouse I/O RNA-Seq Panel

Oncology

Translational Oncology

  • 1+1 Mouse Trial
  • Biomarkers of Response (HuMark)
  • Mouse Clinical Trials (HuTrial)
  • Signatures of Response (HuSignature)

Biomarker Services

  • Flow Cytometry Platform
  • Genomics Services
    • Mouse I/O RNA-Seq Panel
  • Histology and Digital Pathology Platform

Pharmacology and Bioanalytical Services

  • ADME & Physicochem
  • Bioanalysis Studies
  • FACS Platform
  • In Vivo PK/PD
  • NHP Immuno-Safety
  • Structural Biology
  • Target Validation

Oncology Databases

  • HuBase
  • MuBase
  • OncoExpress
  • XenoBase

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