Bladder Cancer PDX Models

With many new agents under development, including immuno- and targeted therapies, predictive research models such as patient-derived xenografts (PDX) are required for preclinical evaluation. PDX models are proven to be highly predictive models for preclinical drug assessment. The CrownBio bladder cancer PDX collection consists of a wide range of models, including subcutaneous and orthotopic models to more closely recapitulate the tumor microenvironment and models carrying FGFR3 and TSC1 mutations. More

PDX offer the most translational preclinical model for efficacy screening in cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, PDX models reflect the heterogeneity and diversity of the human patient population. PDX give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials. CrownBio’s HuPrime® PDX models are well characterized for pathology, growth characteristics, and are also genetically/genomically annotated for gene expression, gene copy number, mutations, and fusions.
MODEL NUMBERCANCER SUBTYPE # per page
BL0597 SCCCLICK TO VIEW
BL2350 ADCCLICK TO VIEW
BL2393 SarcomaCLICK TO VIEW
BL3249 SCCCLICK TO VIEW
BL3325 ADCCLICK TO VIEW
BL3338 ADCCLICK TO VIEW
BL3479 NACLICK TO VIEW
BL3578 NACLICK TO VIEW
BL5001 TCCCLICK TO VIEW
BL5003 TCCCLICK TO VIEW
BL5006 TCCCLICK TO VIEW
BL5007 TCCCLICK TO VIEW
BL5368 NACLICK TO VIEW
BL5384 NACLICK TO VIEW
BL5420 NACLICK TO VIEW
BL5422 NACLICK TO VIEW
BL5425 NACLICK TO VIEW
BL5428 NACLICK TO VIEW
BL9200 NACLICK TO VIEW
BL9208 NACLICK TO VIEW