Patient-Derived Xenograft Models of Colorectal Cancer

Robust, well characterized preclinical models are essential for the advancement of targeted therapies for colorectal cancer. Colon cancer Patient-derived xenograft (PDX) models display a true representation of the human genetic and phenotypic heterogeneity seen in patient populations and provide the most accurate approach to predicting an agent’s efficacy prior to entering the clinic. CrownBio has one of the largest collections of Colorectal cancer PDX models, including subcutaneous and orthotopic models to more closely recapitulate the tumor microenvironment. More

Benefits of CrownBio’s Colon cancer Patient-derived xenograft model research

Our Colorectal cancer Patient-derived xenograft models offer the most translational preclinical model for efficacy screening in Colon cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, Patient derived xenograft reflects the heterogeneity and diversity of the human patient population. Colong cancer (PDX) model will give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials. CrownBio’s HuPrime® Rectal cancer PDX models are well characterized for pathology, growth characteristics, and are also genetically/genomically annotated for gene expression, gene copy number, mutations, and fusions.

MODEL NUMBERCANCER SUBTYPE # per page
CR0004 ADCCLICK TO VIEW
CR0010 ADCCLICK TO VIEW
CR0012 ADCCLICK TO VIEW
CR0024 ADCCLICK TO VIEW
CR0028 ADCCLICK TO VIEW
CR0029 ADCCLICK TO VIEW
CR0047 ADCCLICK TO VIEW
CR0126 Mucinous adenocarcinomaCLICK TO VIEW
CR0133 ADCCLICK TO VIEW
CR0146 ADCCLICK TO VIEW
CR0150 ADCCLICK TO VIEW
CR0170 ADCCLICK TO VIEW
CR0193 ADCCLICK TO VIEW
CR0196 ADCCLICK TO VIEW
CR0205 ADCCLICK TO VIEW
CR0231 ADCCLICK TO VIEW
CR0245 ADC, MucinousCLICK TO VIEW
CR0455 ADCCLICK TO VIEW
CR0460 ADCCLICK TO VIEW
CR0560 ADCCLICK TO VIEW