Esophageal Cancer PDX Models

Esophageal cancer is the 6th most common cause of cancer related deaths which drives a need for a better understanding of the underlying mechanisms behind the disease through preclinical models. Patient-derived xenograft (PDX) models provide a true representation of the human heterogeneity and can be used to better understand these mechanisms in relation to the development of new therapies. CrownBio has a large selection of well characterized esophageal cancer PDX models, including models with EGFR amplification. More

PDX offer the most translational preclinical model for efficacy screening in cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, PDX models reflect the heterogeneity and diversity of the human patient population. PDX give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials. CrownBio’s HuPrime® PDX models are well characterized for pathology, growth characteristics, and are also genetically/genomically annotated for gene expression, gene copy number, mutations, and fusions.
MODEL CANCER TYPE SUBTYPE models per page
ES0026Esophageal CancerESCCVIEW MODEL
ES0042Esophageal CancerESCCVIEW MODEL
ES0110Esophageal CancerESCCVIEW MODEL
ES0136Esophageal CancerESCCVIEW MODEL
ES0141Esophageal CancerESCCVIEW MODEL
ES0147Esophageal CancerESCCVIEW MODEL
ES0148Esophageal CancerESCCVIEW MODEL
ES0159Esophageal CancerESCCVIEW MODEL
ES0168Esophageal CancerESCCVIEW MODEL
ES0172Esophageal CancerESCCVIEW MODEL