Head and Neck Cancer PDX Models

Head and neck cancers start in the organs of the head or neck such as mouth, throat, and lips. As with all cancer treatment development, a predictive preclinical model is needed for therapy evaluation. Patient-derived xenograft (PDX) models present a true representation of the human heterogeneity and provide the most accurate approach to predicting an agent’s efficacy prior to entering the clinic. CrownBio has a large collection of head and neck cancer PDX models, including many with EGFR amplification. More

PDX offer the most translational preclinical model for efficacy screening in cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, PDX models reflect the heterogeneity and diversity of the human patient population. PDX give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials. CrownBio’s HuPrime® PDX models are well characterized for pathology, growth characteristics, and are also genetically/genomically annotated for gene expression, gene copy number, mutations, and fusions.
MODEL NUMBER CANCER SUBTYPE # per page
HN0366 HNSCCCLICK TO VIEW
HN0586 HNSCCCLICK TO VIEW
HN0626 HNSCCCLICK TO VIEW
HN0635 HNSCCCLICK TO VIEW
HN0696 HNSCCCLICK TO VIEW
HN1391 HNSCCCLICK TO VIEW
HN1420 HNSCCCLICK TO VIEW
HN1774 NACLICK TO VIEW
HN1972 HNSCCCLICK TO VIEW
HN2167 HNSCCCLICK TO VIEW
HN2170 HNSCCCLICK TO VIEW
HN2174 HNSCCCLICK TO VIEW
HN2195 HNSCCCLICK TO VIEW
HN2221 HNSCCCLICK TO VIEW
HN2222 HNSCCCLICK TO VIEW
HN2400 N/ACLICK TO VIEW
HN2447 SCCCLICK TO VIEW
HN2448 HNSCCCLICK TO VIEW
HN2574 SCCCLICK TO VIEW
HN2575 SCCCLICK TO VIEW