Liver Cancer PDX Models

Liver cancer is the second leading cause of cancer-related deaths worldwide. Due to this, there is a need for more predictive and relevant preclinical models to provide better insights into clinical outcomes when evaluating new cancer therapies. Patient-derived xenograft (PDX) models display a true representation of the human genetic and phenotypic heterogeneity seen in patient populations and provide the most accurate approach to predicting an agent’s efficacy prior to entering the clinic. CrownBio’s collection consists of a large number of liver cancer PDX models, including several orthotopic models to more closely recapitulate the tumor microenvironment. More

PDX offer the most translational preclinical model for efficacy screening in cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, PDX models reflect the heterogeneity and diversity of the human patient population. PDX give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials. CrownBio’s HuPrime® PDX models are well characterized for pathology, growth characteristics, and are also genetically/genomically annotated for gene expression, gene copy number, mutations, and fusions.
MODEL NUMBER CANCER SUBTYPE # per page
LI0050 HCCCLICK TO VIEW
LI0334 HCCCLICK TO VIEW
LI0348 HCCCLICK TO VIEW
LI0574 HCCCLICK TO VIEW
LI0612 HCCCLICK TO VIEW
LI0752 HCCCLICK TO VIEW
LI0801 HCCCLICK TO VIEW
LI0941 SCCCLICK TO VIEW
LI1004 HCCCLICK TO VIEW
LI1005 HCCCLICK TO VIEW
LI1025 HCCCLICK TO VIEW
LI1035 HCCCLICK TO VIEW
LI1037 HCCCLICK TO VIEW
LI1054 HCCCLICK TO VIEW
LI1055 HCCCLICK TO VIEW
LI1057 HCCCLICK TO VIEW
LI1058 HCCCLICK TO VIEW
LI1068 HCCCLICK TO VIEW
LI1069 HCCCLICK TO VIEW
LI1074 HCCCLICK TO VIEW