Liver Cancer PDX Models

Liver cancer is the second leading cause of cancer related deaths worldwide. Due to this, there is a need for more predictive and relevant preclinical models to provide better insights into clinical outcomes when evaluating new cancer therapies. Patient-derived xenograft (PDX) models display a true representation of the human genetic and phenotypic heterogeneity seen in patient populations and provide the most accurate approach to predicting an agent’s efficacy prior to entering the clinic. CrownBio’s collection consists of a large number of liver cancer PDX models, including several orthotopic models to more closely recapitulate the tumor microenvironment. More

PDX offer the most translational preclinical model for efficacy screening in cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, PDX models reflect the heterogeneity and diversity of the human patient population. PDX give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials. CrownBio’s HuPrime® PDX models are well characterized for pathology, growth characteristics, and are also genetically/genomically annotated for gene expression, gene copy number, mutations, and fusions.
MODELCANCER TYPESUBTYPE models per page
LI1081Liver CancerHCCVIEW MODEL
LI1088Liver CancerHCCVIEW MODEL
LI1097Liver CancerHCCVIEW MODEL
LI1098Liver CancerHCCVIEW MODEL
LI1549Liver CancerNAVIEW MODEL
LI1646Liver CancerHCCVIEW MODEL
LI2169Liver CancerHCCVIEW MODEL
LI3205Liver CancerHCCVIEW MODEL
LI5129Liver CancerHCCVIEW MODEL
LI5130Liver CancerHCCVIEW MODEL