Patient-Derived Xenograft Models of Lung Cancer

Lung cancer is the most common type of cancer worldwide, accounting for 13% of the total number of new diagnoses and is classified according to histological type by the size and appearance of cells: non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Given the prominence of lung cancer diagnosed in the population, predictive preclinical models are essential for treatment development. Our lung cancer models are known to be the most predictive and provide the most accurate approach to evaluating an agents efficacy prior to entering the clinic. CrownBio offers a large collection of over 300 well characterized models including 70 SCLC models, as well as primary and metastatic models. More

Benefits of CrownBio’s Lung Cancer PDX Models

Our lung cancer patient-derived xenograft models offer the most translational preclinical model for efficacy screening in cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, patient derived xenografts reflect the heterogeneity and diversity of the human patient population. PDX give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials. CrownBio’s HuPrime® PDX models are well characterized for pathology, growth characteristics, and are also genetically/genomically annotated for gene expression, gene copy number, mutations, and fusions.

MODEL NUMBER CANCER SUBTYPE # per page
LU0009 NSCLC, SCCCLICK TO VIEW
LU0038 NSCLC, SCCCLICK TO VIEW
LU0299 NSCLC, SCCCLICK TO VIEW
LU0330 NSCLC, SCCCLICK TO VIEW
LU0350 NSCLC, SCCCLICK TO VIEW
LU0357 NSCLC, SCCCLICK TO VIEW
LU0367 NSCLC, SCCCLICK TO VIEW
LU0377 NSCLC, ADCCLICK TO VIEW
LU0387 NSCLC, ADCCLICK TO VIEW
LU0395 NSCLC, SCCCLICK TO VIEW
LU0697 NSCLC, SCCCLICK TO VIEW
LU0741 NSCLC, SCCCLICK TO VIEW
LU0743 NSCLC, SCCCLICK TO VIEW
LU0748 NSCLC, SCCCLICK TO VIEW
LU0755 NSCLC, SCCCLICK TO VIEW
LU0858 NSCLC, SCCCLICK TO VIEW
LU0860 NeurofibromaCLICK TO VIEW
LU0861 NSCLC, SCCCLICK TO VIEW
LU0876 NSCLC, SCCCLICK TO VIEW
LU0884 NSCLC, SCCCLICK TO VIEW