Uterine Cancer PDX Models

Patient-derived xenograft (PDX) models display a true representation of the human heterogeneity of gynecologic malignancies and provide the most accurate approach to predicting an agents efficacy prior to entering the clinic. The CrownBio uterine cancer PDX collection consists of several models including ER+ and estrogen dependent models. More

PDX offer the most translational preclinical model for efficacy screening in cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, PDX models reflect the heterogeneity and diversity of the human patient population. PDX give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials. CrownBio’s HuPrime® PDX models are well characterized for pathology, growth characteristics, and are also genetically/genomically annotated for gene expression, gene copy number, mutations, and fusions.
MODEL NUMBER CANCER SUBTYPE # per page
UT14024 NACLICK TO VIEW
UT14026 NACLICK TO VIEW
UT3617 EndometrialCLICK TO VIEW
UT3618 NACLICK TO VIEW
UT3759 EndometrialCLICK TO VIEW
UT3778 EndometrialCLICK TO VIEW
UT5317 Endometrial, (ER+)CLICK TO VIEW
UT5318 Endometrial, (ER-)CLICK TO VIEW
UT5319 Endometrial, (ER+)CLICK TO VIEW
UT5320 Endometrial, (ER-)CLICK TO VIEW
UT5321 Endometrial, (ER+)CLICK TO VIEW
UT5322 EndometrialCLICK TO VIEW
UT5324 ADCCLICK TO VIEW
UT5325 ADCCLICK TO VIEW