• July 10, 2019

    Colon-26

    Synonyms: MC26, MC-26, Colon 26, Colon26, C-26, C26 Colon-26 model is a mouse colon adenocarcinoma cell line derived from a tumor induced in BALB/c mice by single rectal application of N-nitroso-N-methylurethane (NMU)(1). It is a cachexic model and is hence commonly used in cachexia research. At CrownBio, the Colon-26 model is offered as a subcutaneous […]

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  • July 10, 2019

    MC38

    Synonyms: MC-38, MCA-38, MCA 38, MCA38, Mouse Colon 38, Murine Carcinoma-38, Colon 38, Colon-38, Colon38, C38 MC38 is derived from a colon tumor in a C57BL/6 mouse following long-term exposure to 1,2-dimethylhydrazine dihydrochloride (DMH)(1). It is one of the most popularly used model for the assessment of anti-cancer immunotherapies and is fit for the evaluation […]

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  • July 10, 2019

    CT26.WT

    Synonyms: CT-26, CT26 CT26.WT was cloned from an N-nitroso-N-methylurethane (NMU) induced, undifferentiated colon carcinoma murine cell line. The cell line has an H-2d haplotype and can be grown in the BALB/c mouse strain. As a mainstay model for evaluating surrogate and cross reactive therapeutics, a vast array of historical data is available. In addition to […]

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