July 10, 2019
Synonyms: Cloudman S91 melanoma clone M-3, CLONE M3, M3 Clone M-3, Cloudman M3 Clone M-3 is a mouse melanoma cell line derived from a Cloudman S91 melanoma in a (C X DBA) F1 male mouse(1). The model is suitable for the evaluation of efficacy and PD of I/O agents. At CrownBio, the Clone M-3 model […]
July 10, 2019
Synonyms: B16/BL6, B16 BL6, B16BL6, B16BL-6, BL6, BL-6, B16-F10-BL6 B16-BL6 is a murine cell line of melanoma, which was derived from the B16-F10 model for its more tissue-invasive property (1). The model is useful for the efficacy and PD assessment of anti-cancer therapeutics. At CrownBio, the B16-BL6 model is available as subcutaneous and metastatic models.
July 10, 2019
Synonyms: B16/F10, B16 F10, B16F10, B16 melanoma F10 B16-F10 is a mouse melanoma cell line, which was derived from the pulmonary melanoma nodule from the tenth serial passage of the B16-F10 parent cell line in C57BL/6 mice(1). The model is commonly used for the efficacy and PD evaluation of surrogate and cross-reactive I/O agents. At […]
July 10, 2019
Synonyms: B16/F1, B16 F1, B16F1 B16-F1 is a murine cell line of melanoma, which was derived from the pulmonary melanoma nodule from the first serial passage of B16-F0 parent cell line in C57BL/6 mice(1). The model is suited for the evaluation of anti-cancer immunotherapy efficacy and PD. At CrownBio, the B16-F1 model has been established […]
July 10, 2019
Synonyms: B16/F0, B16F0 B16-F0 is a mouse melanoma cell line, which can be grown in C57BL/6 mice. The model is suited for the assessment of surrogate and cross-reactive immuno-oncology agent efficacy and PD. At CrownBio, the B16-F0 model is available as a subcutaneous model.