Synonyms: B16/BL6, B16 BL6, B16BL6, B16BL-6, BL6, BL-6, B16-F10-BL6
B16-BL6 is a murine cell line of melanoma, which was derived from the B16-F10 model for its more tissue-invasive property (1). The model is useful for the efficacy and PD assessment of anti-cancer therapeutics. At CrownBio, the B16-BL6 model is available as subcutaneous and metastatic models.
Response to Immune Checkpoint Inhibitors
(1) Poste G., Doll J., Hart I.R., Fidler I.J. In vitro selection of murine B16 melanoma variants with enhanced tissue-invasive properties. Cancer Res. 40:1636-1644, 1980.