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Synonyms: B16/F10, B16 F10, B16F10, B16 melanoma F10
B16-F10 is a mouse melanoma cell line, which was derived from the pulmonary melanoma nodule from the tenth serial passage of the B16-F10 parent cell line in C57BL/6 mice(1). The model is commonly used for the efficacy and PD evaluation of surrogate and cross-reactive I/O agents. At CrownBio, the B16-F10 model is offered as subcutaneous and metastatic models.
| Summary | |
|---|---|
| Cancer Type | Melanoma |
| Subtype | N/A |
| Mouse Strain | C57BL/6 |
| TMA | TMA-CP-SY-008 |
(1) Fidler IJ. Biological behavior of malignant melanoma cells correlated to their survival in vivo. Cancer Res. 35: 218-224, 1975.