BR9469

Model Information:

Summary 
Cancer TypeBreast Cancer
SubtypeHER2(-), ER(3+), PR(3+) 
GradeNA
StageNA
EthnicityWestern
GenderNA
Age53
Pathology DiagnosisILC. Cytospin: Atypical cells with round, large nucleus and high N:C ratio. Also contains some benign mesothelial cells and histiocytes.Some K14+ ER and Ki67 are neg in this sample. pericardium, lung, liver metastasis.
Biopsy SitePleural Effusion
Treatment Historyleuprolide 6/2003 to 6/2008; Letrozole 6-2003 to 7/2007; zolendronic acid 6/2003 to 10/2010; Tamoxifen 7/2007 to 3/2008; Aromasin 4/2008 to 6/2008; cyclophosphamide, 5/2008 fluorouracil, methotrexate 6/2008 to 9/2008 Capcitabine 11/2008 to 3/2009; paclitaxel 3/2009 to 9/2009 Abraxane 9/2009 to 11/2009; doxorubicin 11/2009 to 9/2010; carboplatin, gemcitabine 10/2010 to 10/2010
Pathology QCNA
Special FeaturesIHC (P8): HER2(-), ER(3+), PR(3+); estrogen independence (EI), derived from BR9468. ESR1 (Y537S), slight ulceration
Mouse StrainNOD.SCID
TMANA
Viral Status in PDXHPV16-, HPV18-, HIV-, HCV-, HBV-, EBV-
Available InCB_CN
RNA SeqP6
Exome SeqP6

Create Account to View All Model Data

Already Registered? Login