Model Information:

Right lobe of liver: adenocarcinoma, grade II, consider bile duct origin. Peripheral hepatic tissues showed nodular cirrhosis G2~3,S2~3.IHC results: AFP(-), Hepa(-), CK7(+++), CK19(++), CD34(blood vessel +), GP73(++), Thromblin(-), IL-2(-), Ki67(70%+), CD8(2/HPF), OPN(70%+), GS(-), HSP70(+~++), CD151(-), GPC-3(-).

Summary

Cancer Type Cholangiocarcinoma
Subtype ICC
Grade II
Stage NA
Ethnicity Asian
Gender M
Age 37
Pathology Diagnosis

Right lobe of liver: adenocarcinoma, grade II, consider bile duct origin. Peripheral hepatic tissues showed nodular cirrhosis G2~3,S2~3.IHC results: AFP(-), Hepa(-), CK7(+++), CK19(++), CD34(blood vessel +), GP73(++), Thromblin(-), IL-2(-), Ki67(70%+), CD8(2/HPF), OPN(70%+), GS(-), HSP70(+~++), CD151(-), GPC-3(-).

Biopsy Site Liver
Treatment History NA
Pathology QC Poorly differentiated adenocarcinoma (P4, P6); IHC (P5): CK8/18 (3+), AFP (-), CK7 (3+), CA199 (+), EMA (3+), CEA (+)
Special Features MET amplified
Mouse Strain Balb/c nu
TMA NA
Publication NA

Growth Characteristics

Additional Characteristics