Synonyms: MC26, MC-26, Colon 26, Colon26, C-26, C26
Colon-26 model is a mouse colon adenocarcinoma cell line derived from a tumor induced in BALB/c mice by single rectal application of N-nitroso-N-methylurethane (NMU)(1). It is a cachexic model and is hence commonly used in cachexia research. At CrownBio, the Colon-26 model is offered as a subcutaneous model.
|Cancer Type||Colorectal Cancer|
(1) Corbett T.H., Griswold D.P. Jr., Roberts B.J., Peckham J.C., Schabel F.M. Jr. Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure. Cancer Res. 35:2434-2439, 1975.