Model Information:

Adenocarcinoma of colon with part of mucinous adenocarcinoma, moderately differentiated. Tumor cells show columnar with circular or oval nuclear. The tumor forms tubular or nest structures and has an infiltrative growth pattern. Poors of mucin in glandular cavity may be seen. Regional LN: mesenteric LN (5/20).

Summary

Cancer TypeColorectal Cancer
SubtypeADC, mucinous adenocarcinoma
GradeNA
StageNA
EthnicityAsian
GenderF
Age35
Pathology Diagnosis

Adenocarcinoma of colon with part of mucinous adenocarcinoma, moderately differentiated. Tumor cells show columnar with circular or oval nuclear. The tumor forms tubular or nest structures and has an infiltrative growth pattern. Poors of mucin in glandular cavity may be seen. Regional LN: mesenteric LN (5/20).

Biopsy SiteColon
Treatment HistoryNA
Pathology QCModerately differentiated tubular adenocarcinoma, with part of mucinous adenocarcinoma (P3)
Special FeaturesPTPRK-RSPO3 fusion, PIK3CA E545K
Mouse StrainBalb/c nu
TMATMA-HP-CR-033
PublicationMolecular pathology of patient tumors, patient derived xenografts and cancer cell lines; Wnt addiction of genetically defined cancers reversed by PORCN inhibition; Therapeutic Targeting of Tumor-Derived R-Spondin Attenuates B-Catenin Signaling and Tumorigenesis in Multiple Cancer Types; Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function

Growth Characteristics

Additional Characteristics