Synonyms: EL-4, EL 4, E.L.4
EL4 is a mouse thymic lymphoma cell line established by the induction of 9, 10-dimethyl-1,2-benzanthracene (DMBA) in a C57BL mouse. This model can be used to assess I/O treatment efficacy and immuno-PD changes. At CrownBio, the EL4 model is offered subcutaneously as well as systemically (i.v. injected). E.G7-OVA, a derivative of the EL4 model, is also available.
Response to Immune Checkpoint Inhibitors