ES2116

Model Information:

Adenocarcinoma derived from juncture of stomach and esophagus, protruded type, moderately-poorly differentiated, tumor mass: 4cm x 3.5cm. No malignant cells adjacent to esophageal stump and duodenal stump. Regional LN: right cardial LN (0/1), left cardial LN (5/5), LN of lesser curvature (0/5), inferior pyloric LN (0/4), LN of left gastric artery (3/5). IHC results: CD44(+), Cmet(+), EGFR(-), HER2(2+), Ki-67(+50-75%), MMP7(-), P170(weak +), P27(+>75%), P53(-), TOPOII(+25-50%)

Summary  
Cancer Type esophageal-cancer
Subtype EAC
Grade IIIC
Stage T4N1M0,IIIa
Ethnicity Asian
Gender F
Age 63
Pathology Diagnosis Adenocarcinoma derived from juncture of stomach and esophagus, protruded type, moderately-poorly differentiated, tumor mass: 4cm x 3.5cm. No malignant cells adjacent to esophageal stump and duodenal stump. Regional LN: right cardial LN (0/1), left cardial LN (5/5), LN of lesser curvature (0/5), inferior pyloric LN (0/4), LN of left gastric artery (3/5). IHC results: CD44(+), Cmet(+), EGFR(-), HER2(2+), Ki-67(+50-75%), MMP7(-), P170(weak +), P27(+>75%), P53(-), TOPOII(+25-50%)
Biopsy Site Esophagus
Treatment History NA
Pathology QC Moderately to poorly differentiated adenocarcinoma (P1, P6)
Special Features slight BW loss, ERBB2 amplified; FGFR1 slightly amplified (6)
Mouse Strain Balb/c nu
TMA TMA-HP-ES-014
Viral Status in PDX NA
Available In CB_CN
RNA Seq P4
Exome Seq NA

Growth Characteristics

Additional Characteristics

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