Model Information:

Signet-ring cell carcinoma of gastric greater curvature, parts are mucinous adenocarcinoma, protruded type, tumor mass: 3.5cm x 3.5cm x 2cm, infiltrating into gastric wall. Regional LN: LN surround celiac trunk (1/1). IHC results: HER-1(-), HER-2(-), p53(-), p170(-), Ki-67(+ 25~50%), VEGF(+), TopIIa(+<25%), p16(-).

Summary

Cancer TypeGastric Cancer
SubtypeSignet-ring cell carcinoma
GradeNA
StageT2N2M0 III
EthnicityAsian
GenderF
AgeNA
Pathology Diagnosis

Signet-ring cell carcinoma of gastric greater curvature, parts are mucinous adenocarcinoma, protruded type, tumor mass: 3.5cm x 3.5cm x 2cm, infiltrating into gastric wall. Regional LN: LN surround celiac trunk (1/1). IHC results: HER-1(-), HER-2(-), p53(-), p170(-), Ki-67(+ 25~50%), VEGF(+), TopIIa(+<25%), p16(-).

Biopsy SiteStomach
Treatment HistoryNA
Pathology QCSignet-ring cell carcinoma (P0), Mucinous adenocarcinoma (P7).
Special FeaturesMYC amplified
Mouse StrainBalb/c nu
TMATMA-HP-GA-021
PublicationA subset of gastric cancers with EGFR amplification and overexpression respond to cetuximab therapy

Growth Characteristics

Additional Characteristics