Model Information:

Signet-ring cell carcinoma of gastric greater curvature, parts are mucinous adenocarcinoma, protruded type, tumor mass: 3.5cm x 3.5cm x 2cm, infiltrating into gastric wall. Regional LN: LN surround celiac trunk (1/1). IHC results: HER-1(-), HER-2(-), p53(-), p170(-), Ki-67(+ 25~50%), VEGF(+), TopIIa(+<25%), p16(-).

Summary

Cancer Type Gastric Cancer
Subtype Signet-ring cell carcinoma
Grade NA
Stage T2N2M0 III
Ethnicity Asian
Gender F
Age NA
Pathology Diagnosis

Signet-ring cell carcinoma of gastric greater curvature, parts are mucinous adenocarcinoma, protruded type, tumor mass: 3.5cm x 3.5cm x 2cm, infiltrating into gastric wall. Regional LN: LN surround celiac trunk (1/1). IHC results: HER-1(-), HER-2(-), p53(-), p170(-), Ki-67(+ 25~50%), VEGF(+), TopIIa(+<25%), p16(-).

Biopsy Site Stomach
Treatment History NA
Pathology QC Signet-ring cell carcinoma (P0), Mucinous adenocarcinoma (P7).
Special Features MYC amplified
Mouse Strain Balb/c nu
TMA TMA-HP-GA-021
Publication A subset of gastric cancers with EGFR amplification and overexpression respond to cetuximab therapy

Growth Characteristics

Additional Characteristics