Model Information:

Adenocarcinoma of gastric cardia, ulcerative type, poorly differentiated, tumor mass: 9cm x 6cm x 1.5cm, infiltrating into serosa, and accompanied with necrosis and a few lymphocytes deposition. No visible malignant cells adjacent to both stump. Regional LN: cardial LN (0/5), left gastric LN (0/7).

Summary

Cancer TypeGastric Cancer
SubtypeADC
GradeIII
StageT3N0M0 II
EthnicityAsian
GenderM
Age58
Pathology Diagnosis

Adenocarcinoma of gastric cardia, ulcerative type, poorly differentiated, tumor mass: 9cm x 6cm x 1.5cm, infiltrating into serosa, and accompanied with necrosis and a few lymphocytes deposition. No visible malignant cells adjacent to both stump. Regional LN: cardial LN (0/5), left gastric LN (0/7).

Biopsy SiteStomach
Treatment HistoryNA
Pathology QCPoorly differentiated adenocarcinoma with part of papillary formation (P1), moderately to poorly differentiated adenocarcinoma (P6)
Special FeaturesFGFR2 amplified
Mouse StrainBalb/c nu
TMATMA-HP-GA-021
PublicationA subset of gastric cancers with EGFR amplification and overexpression respond to cetuximab therapy; c-Myc alteration determines the therapeutic response to FGFR inhibitors; Preclinical Efficacy of the Auristatin-Based Antibody-Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors

Growth Characteristics

Additional Characteristics