Model Information:

Adenocarcinoma of gastric cardia, ulcerative type, poorly differentiated, tumor mass: 9cm x 6cm x 1.5cm, infiltrating into serosa, and accompanied with necrosis and a few lymphocytes deposition. No visible malignant cells adjacent to both stump. Regional LN: cardial LN (0/5), left gastric LN (0/7).

Summary

Cancer Type Gastric Cancer
Subtype ADC
Grade III
Stage T3N0M0 II
Ethnicity Asian
Gender M
Age 58
Pathology Diagnosis

Adenocarcinoma of gastric cardia, ulcerative type, poorly differentiated, tumor mass: 9cm x 6cm x 1.5cm, infiltrating into serosa, and accompanied with necrosis and a few lymphocytes deposition. No visible malignant cells adjacent to both stump. Regional LN: cardial LN (0/5), left gastric LN (0/7).

Biopsy Site Stomach
Treatment History NA
Pathology QC Poorly differentiated adenocarcinoma with part of papillary formation (P1), moderately to poorly differentiated adenocarcinoma (P6)
Special Features FGFR2 amplified
Mouse Strain Balb/c nu
TMA TMA-HP-GA-021
Publication A subset of gastric cancers with EGFR amplification and overexpression respond to cetuximab therapy; c-Myc alteration determines the therapeutic response to FGFR inhibitors; Preclinical Efficacy of the Auristatin-Based Antibody-Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors

Growth Characteristics

Additional Characteristics