GA0046

Model Information:

Adenocarcinoma derived from juncture of stomach and esophagus in lesser gastric curvature, protrude, ulcerative type, poorly differentiated, tumor mass: 6cm x 5cm x 1.5cm. Malignant cells infiltrating into gastric wall and esophagus. Regional LN: LN of lesser curvature (3/14). IHC results: HER-1(+), HER-2(-), p53(+ 25~50%), p170(-),Ki-67(+, 25-50%), VEGF(++), Top-IIa(+ about 10%), p16(-).

Summary 
Cancer Typegastric-cancer
SubtypeADC
GradeIII
StageT4N1M0 III
EthnicityAsian
GenderF
Age74
Pathology DiagnosisAdenocarcinoma derived from juncture of stomach and esophagus in lesser gastric curvature, protrude, ulcerative type, poorly differentiated, tumor mass: 6cm x 5cm x 1.5cm. Malignant cells infiltrating into gastric wall and esophagus. Regional LN: LN of lesser curvature (3/14). IHC results: HER-1(+), HER-2(-), p53(+ 25~50%), p170(-),Ki-67(+, 25-50%), VEGF(++), Top-IIa(+ about 10%), p16(-).
Biopsy SiteStomach
Treatment HistoryNA
Pathology QCModerately-poorly differentiated adenocarcinoma (P4). IHC (P5): TTF1 (-), CDX2 (3+), CK7 (+), CK20 (3+).
Special FeaturesCachexia, Metastatic (subC)
Mouse StrainBalb/c nu
TMATMA-HP-GA-021
Viral Status in PDXNA
Available InCB_CN
RNA SeqP4
Exome SeqP3

Growth Characteristics

Additional Characteristics

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