Synonyms (of parental line): Glioma 261, GLIOMA 261, Glioma-261, GL-261
GL261 is a mouse glioblastoma cell line. The original tumor was induced by intracranial injection of 3-methylcholantrene into C57BL/6 mice(1). GL261 cells were transduced by firefly luciferase gene to generate the reporter line, GL261-luc for the monitoring of disease progression via bioluminescent imaging. The model is suitable for imaging studies and efficacy/PD testing. At CrownBio, the GL261-luc model is offered as both subcutaneous and orthotopic models.
Summary | |
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Cancer Type | Glioma |
Subtype | N/A |
Mouse Strain | C57BL/6 |
TMA | Null |
(1) Szatmari T., Lumniczky K., Desaknai S., Trajcevski S., Hidvegi E.J., Hamada H., Safrany G. Detailed characterization of the mouse glioma 261 tumor model for experimental glioblastoma therapy. Cancer Sci. 97:546-553, 2006.