The chimeric CD137 construct consist of human exon 4 – exon 7 region, replacing the mouse coding region by using CRISPR/Cas9 technology. This model is an appropriate platform for human anti-CD137 antibody evaluation.
Summary | |
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Cancer Type | N/A |
Type | Single Knock-In |
Target | Human CD137 |
Mouse Strain | C57BL/6 |