Model Information:

The chimeric CD137 construct consist of human exon 4 – exon 7 region, replacing the mouse coding region by using CRISPR/Cas9 technology. This model is an appropriate platform for human anti-CD137 antibody evaluation.

Summary

TypeSingle Knock-In
TargetHuman CD137
Mouse StrainC57BL/6

Validation of Human Target Expression

Additional Characteristics