The chimeric CD137 construct consist of human exon 4 – exon 7 region, replacing the mouse coding region by using CRISPR/Cas9 technology. This model is an appropriate platform for human anti-CD137 antibody evaluation.
| Summary | |
|---|---|
| Cancer Type | N/A |
| Type | Single Knock-In |
| Target | Human CD137 |
| Mouse Strain | C57BL/6 |
