Model Information:

The chimeric CD137 construct consist of human exon 4 – exon 7 region, replacing the mouse coding region by using CRISPR/Cas9 technology. This model is an appropriate platform for human anti-CD137 antibody evaluation.

Cancer Type N/A
Type Single Knock-In
Target Human CD137
Mouse Strain C57BL/6

Validation of Human Target Expression

Additional Characteristics

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