The chimeric CTLA-4 construct consists of human exon 2 and 3, and murine exons 1 and 4. This model is an appropriate platform for human anti-CTLA-4 antibody evaluation.
| Summary | |
|---|---|
| Cancer Type | N/A |
| Type | Single Knock-In |
| Target | Human CTLA-4 |
| Mouse Strain | C57BL/6 |
