Model Information:

The chimeric CTLA-4 construct consists of human exon 2 and 3, and murine exons 1 and 4. This model is an appropriate platform for human anti-CTLA-4 antibody evaluation.

Summary

TypeSingle Knock-In
TargetHuman CTLA-4
Mouse StrainC57BL/6

Validation of Human Target Expression

Additional Characteristics