The chimeric human/mouse PD-1 gene (h/mPD-1) consisting of human exon 2 which is “knock in” by using CRISPR/Cas9 technology to create homozygous h/mPD-1 HuGEMM C57BL/6 mice. This model is an appropriate platform for human anti-PD-1 antibody evaluation.
| Summary | |
|---|---|
| Cancer Type | N/A |
| Type | Single Knock-In |
| Target | Human PD-1 |
| Mouse Strain | C57BL/6 |
