Model Information:

The chimeric human/mouse PD-1 gene (h/mPD-1) consisting of human exon 2 which is “knock in” by using CRISPR/Cas9 technology to create homozygous h/mPD-1 HuGEMM C57BL/6 mice. This model is an appropriate platform for human anti-PD-1 antibody evaluation.

Cancer TypeN/A
TypeSingle Knock-In
TargetHuman PD-1
Mouse StrainC57BL/6

Validation of Human Target Expression

Additional Characteristics

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