Model Information:

JC is a cell line of the malignant neoplasm of the mouse mammary gland. It is an epithelial-like cell line established from a spontaneous primary mammary adenocarcinoma along the milk line(1). The model offers a suitable platform for the efficacy and PD evaluation of single and combination I/O agent therapies. At CrownBio, the JC model is offered as a subcutaneous model in the flank.

Cancer TypeBreast Cancer
Mouse StrainBALB/c

Response to Immune Checkpoint Inhibitors

Additional Characteristics

(1) Characterization of a new spontaneously developed murine mammary adenocarcinoma in syngeneic BALB/c hosts. In Vitro Cell. Dev. Biol. 25: 621-626, 1989.

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