JC is a cell line of the malignant neoplasm of the mouse mammary gland. It is an epithelial-like cell line established from a spontaneous primary mammary adenocarcinoma along the milk line(1). The model offers a suitable platform for the efficacy and PD evaluation of single and combination I/O agent therapies. At CrownBio, the JC model is offered as a subcutaneous model in the flank.
Summary | |
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Cancer Type | Breast Cancer |
Subtype | N/A |
Mouse Strain | BALB/c |
TMA | TMA-CP-SY-008 |
(1) Characterization of a new spontaneously developed murine mammary adenocarcinoma in syngeneic BALB/c hosts. In Vitro Cell. Dev. Biol. 25: 621-626, 1989.