Model Information:

Synonyms: KLN 205, KLN-205
KLN205 is a murine lung squamous cell carcinoma cell line, originally obtained from the Nettesheim lung carcinoma in DBA/2 mice(1). The model enables the evaluation of anti-cancer immunotherapy response and immuno-PD changes. At CrownBio, the KLN205 model is offered as a subcutaneous model.


Cancer Type Lung Cancer
Subtype N/A
Mouse Strain DBA/2

Response to Immune Checkpoint Inhibitors

Additional Characteristics

(1) Kaneko T, LePage GA. Growth characteristics and drug responses of a murine lung carcinoma in vitro and in vivo. Cancer Res. 38: 2084-2090, 1978.