Model Information:

Synonyms: MBT2, Mouse Bladder Tumor line-2
MBT-2 is a mouse bladder transitional cell carcinoma cell line produced by the serial transplantation of a FANFT-induced tumor in mice. This cell line can be grown in C3H/He mice. MBT-2 is useful for the evaluation of efficacy and pharmacodynamic changes post immunotherapy treatment. At CrownBio, the MBT-2 in vivo model is available as a subcutaneous model.

Summary

Cancer Type Bladder Cancer
Subtype N/A
Mouse Strain C3H
TMA TMA-CP-SY-008

Response to Immune Checkpoint Inhibitors

Additional Characteristics