Model Information:

This strain carries a conditional mutant constitutive deletion of Trp53 and conditional knock out of PTEN (PTENflox/flox). PTEN was knocked out upon injecting adeno-cre to the prostate at 6 weeks of age, which resulted in a prostate tumor ~4 months later.

Summary

Cancer Type Prostate Cancer
Mutations PTENFlox/Flox; P53-/-
Biopsy Site Prostate
Pathology QC LipoSA-Sarcoma (P1)
Mouse Strain C57BL/6

Growth Characteristics

Additional Characteristics