Model Information:

This strain carries a conditional mutant KRAS (G12D), a conditional knockout PTEN (PTENflox/flox) and a cre driven by the probasin promoter.

Summary

Cancer TypeProstate Cancer
MutationsProbasin-cre,Pten flox/flox, Kras(G12D)
Biopsy SiteProstate
Pathology QCSarcomatoid carcinoma with massive necrosis (P0)
Mouse StrainC57BL/6

Growth Characteristics

Additional Characteristics