mSA6055

Model Information:

This strain carries a conditional mutant Kras (KrasLSL-G12D/WT) and conditional knock out of PTEN (PTENflox/flox). G12D mutant Kras was activated and PTEN was knocked out upon administrating adeno-cre to the lung by inhalation at 6 weeks of age, which resulted in lung cancer approximately 8 weeks later.

Summary  
Cancer Type Sarcoma
Mutations KRAS (G12D); PtenFlox/Flox
Biopsy Site Lung
Pathology QC Osteosarcoma (P1, P6, Pa)
Mouse Strain C57BL/6

Growth Characteristics

Additional Characteristics

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