Model Information:

This strain carries a conditional mutant Kras (KrasLSL-G12D/WT) and a conditional knock out of PTEN (PTENflox/flox). G12D mutant Kras was activated and PTEN was knocked out upon administrating adeno-cre in the prostate. This tumor developed in the suture position approximately 6 months after injection of adeno-cre.

Cancer Type sarcoma
Mutations KRAS (G12D); PtenFlox/Flox
Biopsy Site Enterocoelia (near the suture).
Pathology QC Osteosarcoma (P1, Pa)
Mouse Strain C57BL/6

Growth Characteristics

Additional Characteristics

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