Model Information:

This strain carries a conditional mutant constitutive deletion of Trp53 and conditional knock out of PTEN (PTENflox/flox). The mouse was injected with adeno-cre to the prostate at 6 weeks of age. Unexpectedly, a sarcoma was found approximately 4 months after virus administration instead of a prostate tumor.

Cancer Type Sarcoma
Mutations PTENFlox/Flox; P53-/-
Biopsy Site Forsal side of foreleg
Pathology QC Undifferentiated sarcoma (Pa, P1)
Mouse Strain C57BL/6

Growth Characteristics

Additional Characteristics

Create HuBase Account to View All Model Data

Already Registered? Login