This model was developed from a transgenic mouse with a concomitant inactivation of Ptch1 and Trp53 (Ptch1-/+; p53-/-).
Summary | |
---|---|
Cancer Type | Sarcoma |
Mutations | Ptch1-/+; P53-/- |
Pathology QC | High-grade undifferentiated pleomorphic sarcoma (PA, P4) |
Mouse Strain | C57BL/6 |