This model was developed from a spontaneous tumor located in the left flank of a C57BL/6 mouse with a Trp53 deletion. The primary tumor developed at approximately 18 weeks of age.
|Biopsy Site||Forsal side of foreleg|
|Pathology QC||Malignant peripheral nerve sheath tumor (P1)|
|Publication||Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models|