Model Information:

This model was developed from a subcutaneous primary tumor in a C57BL/6J mouse carrying the ApcMin mutation. This strain is highly susceptible to spontaneous intestinal adenoma formation.

Summary

Cancer Type Skin Cancer
Mutations ApcMin/+
Biopsy Site Forsal side of foreleg
Pathology QC Well differentiated squamous cell carcinoma (P0)
Mouse Strain C57BL/6
TMA TMA-MP-MX-001
Publication Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models
ReferenceA Dominant Mutation That Predisposes to Multiple Intestinal Neoplasia in the Mouse

Growth Characteristics

Additional Characteristics