RM-1 is a murine prostate cancer cell line derived from a Ras+Myc-induced prostate cancer that developed from a urogenital sinus mouse prostate reconstitution in male C57BL/6 mice(1). The model is suited for the efficacy and PD evaluation of immuno-oncology agents. At CrownBio, the RM-1 model is available as a subcutaneous model.
|Cancer Type||Prostate Cancer|
Response to Immune Checkpoint Inhibitors
(1) Thompson TC, et al. Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ. Cell 56(6): 917-930, 1989.